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Diet Doctor Podcast · November 18, 2019 · 52m

Dr. Jason Fung on Fasting and the Obesity Code

Nephrologist Dr. Jason Fung explains the insulin-driven model of obesity and why therapeutic fasting — not just calorie restriction — is necessary to lower persistently elevated insulin levels and reverse type 2 diabetes.

Highlights

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Insulin resistance is the root cause of type 2 diabetes — and fasting is the most direct intervention
Fung: type 2 diabetes is caused by chronically elevated insulin driving progressive insulin resistance. Standard treatment (more insulin, more medication) worsens the underlying problem. Fasting directly lowers insulin levels, allowing resistance to reverse.
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Calorie restriction fails long-term because it doesn't address insulin — metabolic rate drops to match reduced intake
Fung: conventional calorie restriction reduces metabolic rate by 25-40% within months, creating a plateau. Fasting avoids this metabolic adaptation because it maintains counter-regulatory hormones (norepinephrine, growth hormone) that preserve metabolic rate.