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Huberman Lab · March 29, 2026 · 2h 15m

How Hormones Shape Sexual Orientation & Behavior

Dr. Marc Breedlove — neuroscientist on how hormones during prenatal development shape brain structure, sexual orientation, and behavior. The science of why people are who they are — not choice, not environment alone, but prenatal hormone exposure.

Highlights

Prenatal hormones shape brain structure and sexual orientation
Breedlove's research: sexual orientation is shaped primarily by hormone exposure during prenatal brain development, not by choice or upbringing.

Misc

Michigan State neuroscience professor
Prenatal hormone exposure shapes brain development