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All-In Podcast

25 episodes processed

Episodes

# · Apr 10, 2026 · 1h 29m
Chamath Palihapitiya, Jason Calacanis, David Sacks, David Friedberg (solo)

(0:00) Bestie intros: Brad Gerstner joins the show! (4:22) Anthropic blocks Mythos release for security concerns: serious or marketing stunt? (24:07) Are OpenAI and Anthropic trying to kill OpenClaw? Does Anthropic already have market dominance in AI coding?

# · Apr 8, 2026 · 1h 2m
Chamath Palihapitiya, Jason Calacanis, David Sacks, David Friedberg (solo)

(0:00) Jason intros PA Governor Josh Shapiro (1:40) Shapiro's blueprint for PA: pro-growth, pro-freedom, less red tape, prosecuting fraud (13:05) Wealth tax debate, what Dems are getting wrong on business (20:17) 2024 Democratic collapse, future of the party, socialist wing (38:12) How Congress has

# · Apr 6, 2026 · 1h 9m
Chamath Palihapitiya, Jason Calacanis, David Sacks, David Friedberg (solo)

(0:00) Friedberg Intros Palantir's Shyam Sankar and Anduril's Trae Stephens (0:56) Palantir Origins: CIA Analyst Joins 20-Person Startup (2:54) War, Deterrence & Silicon Valley's Defense Tech Taboo (8:39) US vs China: Drone Gap, Shipbuilding & 2027 Taiwan Threat (12:27) Anduril's Arsenal-1 Factory &

# · Apr 3, 2026 · 1h 21m
Chamath Palihapitiya, Jason Calacanis, David Sacks, David Friedberg (solo)

(0:00) Bestie intros! (0:12) SpaceX IPO, the economic opportunity of space: a new industrial frontier (21:00) 2026 IPO explosion, OpenAI down round?

# · Mar 27, 2026 · 1h 20m
Chamath Palihapitiya, Jason Calacanis, David Sacks, David Friedberg (solo)

(0:00) Bestie intros!: Friedberg for Governor of California? (2:25) Anthropic's generational run (15:45) OpenAI: getting focused or panic mode?

# · Mar 26, 2026 · 38m
Bryan Johnson

(0:00) David Friedberg intros Bryan Johnson (0:54) Why Bryan Johnson did 5-MeO-DMT (12:56) What brain scans actually show (18:36) Psychosis, bad trips, and life-altering decisions (26:23) The next frontier: organoids and gene therapy (33:26) GLP-1s, abundance, and human optimization (35:35) The long

# · Mar 23, 2026 · 1h 38m
Chamath Palihapitiya, Jason Calacanis, David Sacks, David Friedberg (solo)

(0:00) Intro live from Nvidia GTC (0:37) CoreWeave CEO, Michael Intrator (32:58) Perplexity CEO, Aravind Srinivas (1:07:11) Mistral CEO, Arthur Mensch (1:18:57) IREN CEO, Daniel Roberts Our episode is sponsored by the New York Stock Exchange - a modern marketplace and exchange for building the futur

# · Mar 23, 2026 · 1h 17m
Chamath Palihapitiya, Jason Calacanis, David Sacks, David Friedberg (solo)

(0:00) Matt Mahan: Why He's Running for Governor (1:51) How California Went From Bad to Worse (12:05) Public Sector Unions & Lobbying in Sacramento (19:05) California's Housing Crisis: Regulation & Fees (34:52) California Energy Crisis: Gas Taxes & Green Policy (43:57) The $1 Trillion Pension Time B

# · Mar 19, 2026 · 1h 6m
Chamath Palihapitiya, Jason Calacanis, David Sacks, David Friedberg (solo)

(0:00) Jensen Huang joins the show!

# · Mar 18, 2026 · 45m
John Fetterman

(0:00) David Friedberg welcomes Senator John Fetterman; SAVE Act thoughts (1:08) The broken Democratic Party: TDS, what he stands for, why the party changed, losing bipartisanship, popularity with Republicans (11:42) Iran exit strategy, NATO allies bail on the US (17:42) Israel's influence, AIPAC, g

# · Mar 17, 2026 · 1h 16m
Chamath Palihapitiya, Jason Calacanis, David Sacks, David Friedberg (solo)

(0:00) Travis Kalanick: Officially exiting stealth mode, what he's been working on (5:52) How to automate the physical world, markets to go after (11:00) Return to self-driving: Tesla, Waymo, and the autonomous race (16:17) Leaving Los Angeles for Austin, the decline of truth and justice in Californ

# · Mar 13, 2026 · 1h 20m
Brad Gerstner

(0:00) The Besties welcome Brad Gerstner!

# · Mar 11, 2026 · 1h
Chamath Palihapitiya, Jason Calacanis, David Sacks, David Friedberg (solo)

(0:00) Jason and Chamath welcome SEC's Paul Atkins and CFTC's Michael Selig (0:53) Atkins on how US markets have changed over his 40 year career (3:04) Top priorities across both agencies: Fixing the IPO drought, crypto regulation, cutting unnecessary rules (8:16) AI trading bots, autonomous hedge f

# · Mar 9, 2026 · 1h 3m
Chamath Palihapitiya, Jason Calacanis, David Sacks, David Friedberg (solo)

(0:00) The Besties welcome legendary Harvard professor Graham Allison (1:14) Iran Conflict: Strategy, Netanyahu's influence, Trump's motivation, redefining Middle East security (11:44) Iran endgame scenarios: Democracy, extremism, second-order effects (21:07) Israel: Is Netanyahu destroying Israel's

# · Mar 7, 2026 · 48m
Chamath Palihapitiya, Jason Calacanis, David Sacks, David Friedberg (solo)

(0:00) Jason intros Prince Reza Pahlavi (1:09) Pahlavi's take on the war and vision for Iran's future, Democracy, and return (8:53) Trump's surrender conditions, core principles, role in transition and potential leadership (17:14) Thoughts on the people and spirit of Iran (21:33) Shervin Pishevar jo

# · Mar 6, 2026 · 1h 23m
Under Secretary

(0:00) The Besties welcome Under Secretary of War Emil Michael (2:30) US war with Iran: Bigger picture and why now?

# · Mar 3, 2026 · 49m
Ray Dalio

(0:00) Friedberg Introduces Ray Dalio (1:29) 5 Forces That Will Decide America's Future (7:26) Why Government Reform Is Nearly Impossible (11:19) Gold vs. Bitcoin (28:16) What Economists Got Wrong About Tariffs (41:11) Is America Heading Towards Collapse?

# · Feb 28, 2026 · 1h 21m
Chamath Palihapitiya, Jason Calacanis, David Sacks, David Friedberg (solo)

(0:00) Bestie intros (1:22) Claude's hit list, SaaS crash, and Citrini's AI letter (30:39) Why Doomer narratives are more popular, valuable new AI jobs (40:19) Understanding the Rate Payer Protection Pledge, what's behind datacenter opposition?

# · Feb 20, 2026 · 1h 47m
Epstein Files Special

(0:00) David Sacks introduces Saagar Enjeti and Michael Tracey (1:04) Reacting to the arrest of Prince Andrew in the UK, Epstein's global finance network (11:24) Who was Jeffrey Epstein, and what is this story really about?

# · Feb 13, 2026 · 1h 13m
Chamath Palihapitiya, Jason Calacanis, David Sacks, David Friedberg (solo)

(0:00) Bestie intros (0:23) AI updates: On-prem comeback, token budgets surpass salaries (19:19) Prediction markets: Super Bowl insider trading, how to police? (28:44) All-In Liquidity: The ultimate investor conference (32:48) CBO report: Death spiral, growth opportunity, or golden age?

# · Feb 10, 2026 · 1h 57m
Chamath Palihapitiya, Jason Calacanis, David Sacks, David Friedberg (solo)

(0:00) From China to Canada (6:13) CZ's Early Career: Shockingly Normal (17:39) First Company in Shanghai (23:08) Discovering Bitcoin (30:11) Going All-In on Crypto (41:27) Founding Binance (1:03:57) The FTX Story: SBF Relationship and Collapse (1:09:46) Facing Biden's Anti-Crypto DOJ (1:25:25) Insi

# · Feb 7, 2026 · 1h 19m
Chamath Palihapitiya, Jason Calacanis, David Sacks, David Friedberg (solo)

(0:00) Besties intros: Brad Gerstner joins the show (3:16) Epstein Files (15:45) SaaS stocks crash out (35:11) Moltbook panic (47:37) Trump selects Kevin Warsh as new Fed Chair, replacing Jerome Powell (1:00:50) SpaceX and xAI merge (1:10:45) Brad's major win with Trump Accounts Follow Brad: Follow

# · Jan 30, 2026 · 1h 30m
Chamath Palihapitiya, Jason Calacanis, David Sacks, David Friedberg (solo)

(0:00) Bestie intros + quick Davos recap (9:55) ICE chaos in Minneapolis: aftermath and reactions to the two recent deaths (45:54) Clawdbot takeover: Jason demos his OpenClawd instances, Kimi K2.5, entering the next phase of AI (1:09:58) De-dollarization, gold and silver ripping (1:20:05) California

# · Jan 25, 2026 · 2h 15m
Chamath Palihapitiya, Jason Calacanis, David Sacks, David Friedberg (solo)

(0:00) Intro (0:50) Circle CEO Jeremy Allaire on stablecoins post-GENIUS Act, interest rate impact, growth in 2026, and the future of money in an AI world (52:33) CrowdStrike CEO George Kurtz on cybersecurity in the AI era, most capable hacker nations, and more (1:17:53) Archer CEO Adam Goldstein on

# · Jan 24, 2026 · 1h 6m
Chamath Palihapitiya, Jason Calacanis, David Sacks, David Friedberg (solo)

(0:00) The Besties introduce Dr. Oz (3:26) Trump's vision for healthcare in America (13:26) AI & self-directed healthcare (30:10) The future of GLP-1s and affordability (35:06) The Medical Fraud Crisis (44:02) California fraud and accountability (56:57) Immigration and addiction Follow Dr.